Protease Inhibitors and Phosphatase Inhibitors
Echelon Biosciences Research Labs Cathepsin B substrate - 10 mg, CAS#: 88937-61-5
Cathepsin B substrate - 10mg , Z-Arg-Arg-AMC Category/Application: Enzyme Substrates This item is non returnable
Sigma Aldrich Fine Chemicals Biosciences Phosphatase Inhibitor Cocktail 2 aqueous solution (dark coloration may develop upon storage, which does not affect the activity)
Phosphatase Inhibitor Cocktail 2 aqueous solution (dark coloration may develop upon storage, which does not affect the activity)
Sigma Aldrich Fine Chemicals Biosciences Protease Inhibitor Cocktail for use with mammalian cell and tissue extracts, DMSO solution, MFCD00677817
Protease Inhibitor Cocktail for use with mammalian cell and tissue extracts, DMSO solution
Enzo Life Sciences Cystatin C (human), (purified) (100 µg)
Alternative name: Cystatin 3, Neuroendocrine basic polypeptide, CysC. Purity: ≥95% (SDS-PAGE). Formulation: Lyophilized from 0.02M ammonium bicarbonate buffer. Source: Isolated from human urine. Long Term Storage: -20°C.
Cayman Chemical ERK InhIbItr 500ug
A cell-permeable inhibitor that binds ERK2 near its docking domain (KD = 5 µM); blocks ERK-specific phosphorylation of Rsk-1 and TCF/Elk-1 but does not affect ERK1/2 phosphorylation by MEK1/2; completely prevents proliferation of several cancer cell lines
Selleck Chemical LLC Belnacasan (VX-765) 10mg 273404-37-8
Belnacasan (VX-765) is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM in a cell-free assay. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Cayman Chemical mP-13 InhIbItr 5mg
A pyrimidine dicarboxamide that selectively inhibits MMP-13 (IC50 = 8 nM); blocks osterix-dependent calcification of matrices in limb bud cells during endochondral ossification
Cayman Chemical FurIn InhIbItr ItrIfluoroa
A selective, irreversible, and cell-permeable competitive inhibitor of proprotein convertases, including furin/SPC1 (Ki = ~1 nM), SPC2/PC2 (Ki = 0.36 nM), SPC3/PC1/PC3 (Ki = 2.0 nM), SPC4/PACE4 (Ki = 3.6 nM), SPC6/PC5/PC6, and SPC7/LPC/PC7/PC8 (Ki = 0.12 nM)
Cayman Chemical CathepsIn G InhIbItr I 500ug
A cathepsin G inhibitor (IC50 = 53 nM); selective for cathepsin G over thrombin, Factor Xa, Factor IXa, plasmin, trypsin, and PR3 (IC50s = >100 µM for all), but also weakly inhibits chymotrypsin; inhibits cathepsin G-induced activation of IL-36 in neutrophil degranulates at 10 µM; reduces CD4+ T cell-induced secretion of IFN-γ and IL-17 in B cells incubated with TTC and also reduces TTC presentation in B cells at 10 µM; decreases the size of neuromyelitis optica lesions and reduces the number of perivascular neutrophils when used in combination with sivelestat in a mouse model of IgG-induced brain injury at 5 UG/animal
Cayman Chemical STAT5 InhIbItr 25mg
A cell-permeable, nonpetidic nicotinoyl hydrazone that selectively suppresses STAT5 by targeting its SH2 domain (IC50 = 47 µM against STAT5β SH2 domain EPO peptide binding activity)
Cayman Chemical HDAC6 InhIbItr 1mg
A potent and selective inhibitor of HDAC6 (IC50 = 36 nM) that poorly blocks other HDAC enzymes; cell permeable, inhibiting the acetylation of tubulin in cells with an IC50 value of 210 nM
Cayman Chemical JAK2 InhIbItr V 10mg
A selective inhibitor of the autophosphorylation of wild type and V617F mutant forms of JAK2, displaying IC50 values between 10 and 30 µM; blocks the proliferation of erythroleukemia cells and human hematopoietic progenitor cells expressing JAK2-V617F
Electron Microscopy Sciences Substrate of Silver Coated 2" Silicon Wafer, P-Type <100>, 50 mm
EMS offers a variety of economically priced coated substrates. All coatings are deposited under vacuum using electron beam evaporation. These high quality substrates are coated with 500 Angstroms (50 nm) of silver, with a thin titanium adhesion layer (2-7 nm) between the glass and silver coating. All substrates are pre-cleaned using an ion source for quality assurance. Autoclavable. P-Type <100> wafer.
Dimensions: 50 mm
Material: Silicon Wafer P/Boron
Electron Microscopy Sciences Substrate of Silver Coated Microscope Slide, 25 x 75 mm
EMS offers a variety of economically priced coated substrates. All coatings are deposited under vacuum using electron beam evaporation. These high quality substrates are coated with 500 Angstroms (50 nm) of silver, with a thin titanium adhesion layer (2-7 nm) between the glass and silver coating. All substrates are pre-cleaned using an ion source for quality assurance. Autoclavable. Packed in a cleanroom. Shipped in slide mailers.
Dimensions: 25 x 75 mm
Material: Soda lime glass
Cayman Chemical IKK2 InhIbItr VI 1mg
A potent, cell-permeable, reversible inhibitor of IKK2 (IC50 = 13 nM); used to evaluate the role of the canonical, IκB-dependent NF-κB signaling pathway in cellular responses